Antimicrobial prophylaxis - Cancer Science

What is Antimicrobial Prophylaxis?

Antimicrobial prophylaxis refers to the preventative use of antibiotics, antifungals, and antivirals to reduce the risk of infections in patients who are at high risk. This approach is particularly relevant for patients undergoing cancer treatment, as their immune systems are often compromised.

Why is it Important in Cancer Patients?

Cancer patients, especially those undergoing chemotherapy or hematopoietic stem cell transplantation (HSCT), are at increased risk of infections due to their weakened immune systems. Prophylactic use of antimicrobials can significantly reduce the incidence of severe infections, which can otherwise lead to treatment delays, increased healthcare costs, and higher mortality.

Who Needs Antimicrobial Prophylaxis?

Not all cancer patients require antimicrobial prophylaxis. It is generally recommended for those who are at high risk of infection. This includes patients with prolonged neutropenia (absolute neutrophil count

Relevant Publications

Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Including Matched Sibling and Alternate Donor Transplants - Adaptations and Outcomes From a Tertiary Care Government Institute in India.

Issue Release: 2024

Compliance with antibiotic therapy guidelines in french paediatric intensive care units: a multicentre observational study.

Issue Release: 2024

Efficacy of postexposure prophylaxis with doxycycline (Doxy-PEP) in reducing sexually transmitted infections: a systematic review and meta-analysis.

Issue Release: 2024

Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis.

Issue Release: 2024

Piperacillin/tazobactam for surgical prophylaxis during pancreatoduodenectomy: meta-analysis.

Issue Release: 2024

Prevalence and genomic-based antimicrobial resistance analysis of Avibacterium paragallinarum isolates in Guangdong Province, China.

Issue Release: 2024

Macrolide resistance among Streptococcus agalactiae during COVID-19 public health emergency in Brazil.

Issue Release: 2024

Cutibacterium Acnes in Spine Surgery: Pathophysiology, Diagnosis, and Treatment.

Issue Release: 2024

Antibacterial efficacy of novel bismuth-silver nanoparticles synthesis on and infection models.

Issue Release: 2024

Orthopedic postoperative infection profile and antibiotic sensitivity of 2038 patients across 24 countries - Call for region and institution specific surgical antimicrobial prophylaxis.

Issue Release: 2024

Antimicrobial stewardship program for gastrointestinal surgeries at a Vietnamese tertiary hospital.

Issue Release: 2024

Infective Endocarditis in North Africa and the Middle East, 1990‒2019: Updates from the Global Burden of Disease Study 2019.

Issue Release: 2024

Therapeutic strategies for uncomplicated cystitis in women.

Issue Release: 2024

Advanced Antimicrobial and Anti-Infective Strategies to Manage Peri-Implant Infection: A Narrative Review.

Issue Release: 2024

Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy?

Issue Release: 2024

Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries.

Issue Release: 2024

Incidence of Surgical Site Infections after Transcervical Thyroidectomy in Patients Given Antibiotics versus those without Antibiotics in a Government Hospital in the Philippines.

Issue Release: 2024

Successful maintenance treatment of disseminated nocardiosis with cerebral abscess in a severely immunocompromised patient allergic to trimethoprim-sulfamethoxazole using moxifloxacin and high-dose minocycline: A case report.

Issue Release: 2024

Pattern of prescriptions and prudent use of antimicrobial in horse practice at a Veterinary Teaching Hospital.

Issue Release: 2024

The effect of ciprofloxacin prophylaxis during haematopoietic cell transplantation on infection episodes, exposure to treatment antimicrobials and antimicrobial resistance: a single-centre retrospective cohort study.

Issue Release: 2024

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