Cytochrome P450 17a1 - Cancer Science

Relevant Publications

Ameliorative effects of elderberry (Sambucus nigra L.) extract and extract-derived monosaccharide-amino acid on H2O2-induced decrease in testosterone-deficiency syndrome in a TM3 Leydig cell.

Issue Release: 2024

Targeted Inhibition of CYP11A1 in Castration-Resistant Prostate Cancer.

Issue Release: 2024

Melatonin alleviates oxidative stress damage in mouse testes induced by bisphenol A.

Issue Release: 2024

New insights into the all-testis differentiation in zebrafish with compromised endogenous androgen and estrogen synthesis.

Issue Release: 2024

Proteomics, modeling, and fluorescence assays delineate cytochrome b residues involved in binding and stimulation of cytochrome P450 17A1 17,20-lyase.

Issue Release: 2024

Ferroptosis: First evidence in premature duck ovary induced by polyvinyl chloride microplastics.

Issue Release: 2024

Use of All-Male cyp17a1-Deficient Zebrafish (Danio rerio) for Evaluation of Environmental Estrogens.

Issue Release: 2024

Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products.

Issue Release: 2024

Updates on Mechanisms of Cytochrome P450 Catalysis of Complex Steroid Oxidations.

Issue Release: 2024

Zinc Oxide Nanoparticles Induced Testicular Toxicity Through Inflammation and Reducing Testosterone and Cell Viability in Adult Male Rats.

Issue Release: 2024

Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).

Issue Release: 2023

Effect of maternal periconceptional undernutrition in sheep on cortisol regulation in offspring from mid-late gestation, through to adulthood.

Issue Release: 2023

[Effect of superfine powder and aqueous extract of Polygonati Rhizoma on rats with natural perimenopausal syndrome].

Issue Release: 2023

Cytochrome P450 enzymes as drug targets in human disease.

Issue Release: 2023

Exploring the Chemical Space of CYP17A1 Inhibitors Using Cheminformatics and Machine Learning.

Issue Release: 2023

Human Cytochrome P450 17A1 Structures with Metabolites of Prostate Cancer Drug Abiraterone Reveal Substrate-Binding Plasticity and a Second Binding Site.

Issue Release: 2023

Artepillin C overcomes apalutamide resistance through blocking androgen signaling in prostate cancer cells.

Issue Release: 2023

Fatal fulminant hepatitis in a patient taking abiraterone acetate: a case report.

Issue Release: 2023

Unraveling Complexities in the Absorption and Disposition Kinetics of Abiraterone via Iterative PBPK Model Development and Refinement.

Issue Release: 2023

Steroid 17α-hydroxylase/17, 20-lyase (cytochrome P450 17A1).

Issue Release: 2023

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