Homologous Recombination Repair Mechanism - Cancer Science

Relevant Publications

A RAD18-UBC13-PALB2-RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells.

Issue Release: 2024

MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions.

Issue Release: 2024

Up-Regulation of Non-Homologous End-Joining by MUC1.

Issue Release: 2024

CDC20 Holds Novel Regulation Mechanism in RPA1 during Different Stages of DNA Damage to Induce Radio-Chemoresistance.

Issue Release: 2024

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.

Issue Release: 2024

RHNO1: at the crossroads of DNA replication stress, DNA repair, and cancer.

Issue Release: 2024

Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions.

Issue Release: 2024

Changes in repair pathways of radiation-induced DNA double-strand breaks at the midblastula transition in Xenopus embryo.

Issue Release: 2024

The deubiquitinating enzyme USP4 regulates BRCA1 stability and function.

Issue Release: 2024

Exploration of poly (ADP-ribose) polymerase inhibitor resistance in the treatment of BRCA1/2-mutated cancer.

Issue Release: 2024

Low-dose ionizing radiation-induced RET/PTC1 rearrangement via the non-homologous end joining pathway to drive thyroid cancer.

Issue Release: 2024

Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response.

Issue Release: 2024

The intersection of homologous recombination (HR) and mismatch repair (MMR) pathways in DNA repair-defective tumors.

Issue Release: 2024

BaP/BPDE suppresses homologous recombination repair in human trophoblast cells to induce miscarriage: The roles of lnc-HZ08.

Issue Release: 2024

Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA.

Issue Release: 2024

Post-therapy emergence of an NBN reversion mutation in a patient with pancreatic acinar cell carcinoma.

Issue Release: 2024

Different Patterns of Platinum Resistance in Ovarian Cancer Cells with Homologous Recombination Proficient and Deficient Background.

Issue Release: 2024

Prokaryotic DNA Crossroads: Holliday Junction Formation and Resolution.

Issue Release: 2024

PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response.

Issue Release: 2024

APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance.

Issue Release: 2024

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