Homology Directed Repair (hdr) - Cancer Science

Relevant Publications

Precision Genome Editing with CRISPR-Cas9.

Issue Release: 2024

Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.

Issue Release: 2024

Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans.

Issue Release: 2024

FecB mutation enhances follicle stimulating hormone sensitivity of granulosa cells by up-regulating the SMAD1/5-USF1-FSHR signaling pathway.

Issue Release: 2024

Generating and testing the efficacy of reagents for CRISPR/Cas9 homology directed repair-based manipulations in Tribolium.

Issue Release: 2024

Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts.

Issue Release: 2024

Simple promotion of Cas9 and Cas12a expression improves gene targeting via an all-in-one strategy.

Issue Release: 2024

CRISPR Ribonucleoprotein-Mediated Precise Editing of Multiple Genes in Porcine Fibroblasts.

Issue Release: 2024

The dCas9-based genome editing in .

Issue Release: 2024

NPAS2 dampens chemo-sensitivity of lung adenocarcinoma cells by enhancing DNA damage repair.

Issue Release: 2024

Increasing Knockin Efficiency in Mouse Zygotes by Transient Hypothermia.

Issue Release: 2024

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells.

Issue Release: 2024

Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency.

Issue Release: 2024

Recombinant Production of Glycoengineered Mucins in HEK293-F Cells.

Issue Release: 2024

Development and immunogenicity evaluation of a quadruple-gene-deleted pseudorabies virus strain.

Issue Release: 2024

Efficient Knock-in by CRISPR/Cas9-mediated homology-directed repair in .

Issue Release: 2024

Next-generation CRISPR/Cas-based ultrasensitive diagnostic tools: current progress and prospects.

Issue Release: 2024

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signaling.

Issue Release: 2024

Comparison of Gene-Editing Approaches for Severe Congenital Neutropenia-Causing Mutations in the Gene.

Issue Release: 2024

Germline variants of homology-directed repair or mismatch repair genes in cervical cancer.

Issue Release: 2024

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Why is Tumor Location Important in Cancer?

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