Knudson Hypothesis - Cancer Science

Relevant Publications

Well-differentiated G1 and G2 pancreatic neuroendocrine tumors: a meta-analysis of published expanded DNA sequencing data.

Issue Release: 2024

Retinoblastoma: present scenario and future challenges.

Issue Release: 2023

Primary mediastinal large B-cell lymphoma is characterized by large-scale copy-neutral loss of heterozygosity.

Issue Release: 2022

Second hit impels oncogenesis of retinoblastoma in patient-induced pluripotent stem cell-derived retinal organoids: direct evidence for Knudson\'s theory.

Issue Release: 2022

Precise CCM1 gene correction and inactivation in patient-derived endothelial cells: Modeling Knudson\'s two-hit hypothesis in vitro.

Issue Release: 2019

Cancerous Protein Network That Inhibits the Tumor Suppressor Function of WW Domain-Containing Oxidoreductase (WWOX) by Aberrantly Expressed Molecules.

Issue Release: 2018

New Insights Into Beclin-1: Evolution and Pan-Malignancy Inhibitor Activity.

Issue Release: 2017

Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex.

Issue Release: 2017

Knudson\'s hypothesis revisited in Indian retinoblastoma patients.

Issue Release: 2015

Age-specific bone tumour incidence rates are governed by stem cell exhaustion influencing the supply and demand of progenitor cells.

Issue Release: 2014

Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.

Issue Release: 2013

Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.

Issue Release: 2012

Cancer models, genomic instability and somatic cellular Darwinian evolution.

Issue Release: 2010

Beyond the Knudson\'s hypothesis in von Hippel-Lindau (VHL) disease-proposing vitronectin as a \"gene modifier\".

Issue Release: 2009

The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophrenia.

Issue Release: 2009

Loss of heterozygosity in endometrial carcinoma.

Issue Release: 2008

A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data.

Issue Release: 2008

Origin of renal cell carcinomas.

Issue Release: 2008

Molecular biology of retinoblastoma.

Issue Release: 2008

Possible mechanisms of disease development in tuberous sclerosis.

Issue Release: 2008

What role do biomarkers play in cancer treatment?

How Do Blister Packs Benefit Cancer Patients?

How to Prepare for Bone Marrow Aspiration?

What are the Benefits of Telemedicine in Cancer Care?

Which Types of Cancer Are Most Commonly Associated with Dysphagia?

How do Keratins Affect Tumor Behavior?

Which Cancers are Associated with MSI-H?

What are the Challenges in Using Natural Compounds for Cancer Treatment?

How is Processed Meat Linked to Cancer?

Why is Tumor Location Important in Cancer?

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