Mps1 Inhibitors - Cancer Science

Relevant Publications

TTK inhibitor OSU13 promotes immunotherapy responses by activating tumor STING.

Issue Release: 2024

Chromosomal instability induced in cancer can enhance macrophage-initiated immune responses that include anti-tumor IgG.

Issue Release: 2024

Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase.

Issue Release: 2024

Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer.

Issue Release: 2024

Inhibitor of cardiolipin biosynthesis-related enzyme MoGep4 confers broad-spectrum anti-fungal activity.

Issue Release: 2024

Hijacking monopolar spindle 1 (MPS1) for various cancer types by small molecular inhibitors: Deep insights from a decade of research and patents.

Issue Release: 2024

Development of MPS1 Inhibitors: Recent Advances and Perspectives.

Issue Release: 2023

Community detection in empirical kinase networks identifies new potential members of signalling pathways.

Issue Release: 2023

Structure-Aided Identification of an Inhibitor Targets Mps1 for the Management of Plant-Pathogenic Fungi.

Issue Release: 2023

Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer.

Issue Release: 2023

[Progress in the Study of Spindle Assembly Checkpoint in Lung Cancer].

Issue Release: 2023

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca nanoparticles underlies distinct gene therapy effect in ovarian cancer.

Issue Release: 2022

Design, synthesis and biological evaluation of a new class of 7H-pyrrolo[2,3-d]pyrimidine derivatives as Mps1 inhibitors for the treatment of breast cancer.

Issue Release: 2022

Designing of kinase hinge binders: A medicinal chemistry perspective.

Issue Release: 2022

Computational Biology Dynamics of Mps1 Kinase Molecular Interactions with Isoflavones Reveals a Chemical Scaffold with Potential to Develop New Therapeutics for the Treatment of Cancer.

Issue Release: 2022

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor.

Issue Release: 2022

Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death.

Issue Release: 2021

Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells.

Issue Release: 2021

Studies of Interaction Mechanism between Pyrido [3,4-] Pyrimidine Inhibitors and Mps1.

Issue Release: 2021

Future prospects for mitosis-targeted antitumor therapies.

Issue Release: 2021

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Which Types of Cancer Are Most Commonly Associated with Dysphagia?

How do Keratins Affect Tumor Behavior?

Which Cancers are Associated with MSI-H?

What are the Challenges in Using Natural Compounds for Cancer Treatment?

How is Processed Meat Linked to Cancer?

Why is Tumor Location Important in Cancer?

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