Radiofrequency treatments - Cancer Science

What is Radiofrequency Treatment?

Radiofrequency treatment, also known as Radiofrequency Ablation (RFA), is a minimally invasive procedure used to destroy cancer cells. It employs high-frequency electrical currents to generate heat, which targets and ablates abnormal tissues. RFA is mainly used for tumors that are not amenable to surgical removal.

How Does It Work?

During RFA, a needle-like probe is inserted into the tumor under imaging guidance such as ultrasound, CT, or MRI. Once in position, the probe emits high-frequency electrical currents that produce localized heat, destroying the cancer cells. The heat also helps in sealing blood vessels, minimizing bleeding during the procedure.

Which Types of Cancer Can Be Treated with RFA?

RFA is commonly used to treat liver cancer, both primary (hepatocellular carcinoma) and secondary (metastatic liver cancer). It is also used for kidney tumors, lung cancer, and certain bone cancers. In some cases, it is used for palliative care to relieve symptoms in advanced cancer stages.

Who is a Candidate for RFA?

Candidates for RFA are typically patients who have small to medium-sized tumors, usually less than 5 cm in diameter. It is an option for patients who cannot undergo surgery due to other health conditions or when the tumor is in a location that makes surgical removal risky. It is also considered for patients who have had multiple recurrent tumors.

What are the Advantages of RFA?

RFA offers several advantages over traditional surgical methods. These include:
Minimally invasive with shorter recovery times
Reduced risk of complications
Can be performed on an outpatient basis
Effective in controlling pain and symptoms
Low risk of bleeding and infection

What are the Risks and Side Effects?

While RFA is generally considered safe, it does come with potential risks and side effects. These can include:
Infection at the insertion site
Internal bleeding
Damage to surrounding tissues and organs
Post-ablation syndrome, which includes flu-like symptoms
Recurrence of cancer

How Effective is RFA?

The effectiveness of RFA varies, depending on the type and stage of cancer, the size and location of the tumor, and the patient's overall health. Studies have shown that RFA can achieve complete destruction of small tumors in the liver and other organs, with success rates ranging from 50% to 90%. It is most effective for tumors less than 3 cm in diameter.

What is the Recovery Process Like?

The recovery process for RFA is typically quick. Most patients can return to normal activities within a week. Pain and discomfort at the insertion site are common but usually manageable with over-the-counter pain relievers. Follow-up imaging tests are required to monitor the treated area and assess the effectiveness of the procedure.

Future Directions and Research

Ongoing research is focused on improving the precision and efficacy of RFA. Innovations such as robotic-assisted procedures and combination therapies involving RFA and other treatments like chemotherapy or immunotherapy are being explored. These advancements aim to expand the applicability of RFA to a broader range of cancers and improve patient outcomes.



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