Ras Raf Mek Erk Pathway - Cancer Science

Relevant Publications

Rosmarinic acid activates the Ras/Raf/MEK/ERK signaling pathway to regulate CD8+ T cells and autophagy to clear Chlamydia trachomatis in reproductive tract-infected mice.

Issue Release: 2024

Epigallocatechin-3-gallate inhibits osteogenic differentiation of vascular smooth muscle cells through the transcription factor JunB.

Issue Release: 2024

Britanin - a beacon of hope against gastrointestinal tumors?

Issue Release: 2024

Targeting BRAF pathway in low-grade serous ovarian cancer.

Issue Release: 2024

Case report: Dual dabrafenib and trametinib therapy for treating BRAF V600E mutated lung adenocarcinoma with BRCA2 germline mutation post multiline progression.

Issue Release: 2024

Multitargeting HDAC Inhibitors Containing a RAS/RAF Protein Interfering Unit.

Issue Release: 2024

Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome.

Issue Release: 2024

Huanglian Jiedu decoction alleviates neurobehavioral damage in mice with chronic alcohol exposure through the RAS-RAF-MEK-ERK pathway.

Issue Release: 2024

Low protein expression of LZTR1 in hepatocellular carcinoma triggers tumorigenesis activating the RAS/RAF/MEK/ERK signaling.

Issue Release: 2024

Peptidomic analysis reveals novel peptide PDLC promotes cell proliferation in hepatocellular carcinoma via Ras/Raf/MEK/ERK pathway.

Issue Release: 2024

Preclinical evaluation of avutometinib and defactinib in high-grade endometrioid endometrial cancer.

Issue Release: 2024

miR-451a suppresses the proliferation and migration of high-grade serous ovarian cancer by targeting RAB5A through the Ras/Raf/MEK/ERK pathway.

Issue Release: 2024

Novel RAF-directed approaches to overcome current clinical limits and block the RAS/RAF node.

Issue Release: 2024

The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.

Issue Release: 2024

KRAS is a molecular determinant of platinum responsiveness in glioblastoma.

Issue Release: 2024

Exploiting BRAF mutations in the therapeutic approach towards oral and maxillofacial tumors.

Issue Release: 2024

Huanglian Jiedu decoction alleviates neurobehavioral damage in mice with chronic alcohol exposure through the RAS-RAF-MEK-ERK pathway.

Issue Release: 2024

CircRAPGEF5 acts as a modulator of RAS/RAF/MEK/ERK signaling during colorectal carcinogenesis.

Issue Release: 2024

Targeting RAF dimers in RAS mutant tumors: From biology to clinic.

Issue Release: 2024

Preclinical in vitro and in vivo activity of the RAF/MEK clamp avutometinib in combination with FAK inhibition in uterine carcinosarcomas.

Issue Release: 2024

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