Strand Slippage - Cancer Science

Relevant Publications

Stick-slip unfolding favors self-association of expanded mRNA.

Issue Release: 2024

Excited-Ground-State Transition of the RNA Strand Slippage Mechanism Captured by the Base-Specific Force Field.

Issue Release: 2024

Mechanical Stability and Unfolding Pathways of Parallel Tetrameric G-Quadruplexes Probed by Pulling Simulations.

Issue Release: 2024

Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by β-strand slippage.

Issue Release: 2024

Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer.

Issue Release: 2023

Revisiting mutagenesis at non-B DNA motifs in the human genome.

Issue Release: 2023

Complexity of Guanine Quadruplex Unfolding Pathways Revealed by Atomistic Pulling Simulations.

Issue Release: 2023

Partners in crime: Tbf1 and Vid22 promote expansions of long human telomeric repeats at an interstitial chromosome position in yeast.

Issue Release: 2022

Turnip mosaic virus transcriptional slippage dynamics and distribution in RNA subpopulations.

Issue Release: 2022

Slippage at the Initiation of RNA Synthesis by Qβ Replicase Results in a Periodic PolyG Pattern.

Issue Release: 2022

Migrating bubble synthesis promotes mutagenesis through lesions in its template.

Issue Release: 2022

The optimal strategy balancing risk and speed predicts DNA damage checkpoint override times.

Issue Release: 2022

Structural and mechanistic basis of reiterative transcription initiation.

Issue Release: 2022

Mechanism of transcription initiation and primer generation at the mitochondrial replication origin OriL.

Issue Release: 2021

A Small Molecule Exploits Hidden Structural Features within the RNA Repeat Expansion That Causes c9ALS/FTD and Rescues Pathological Hallmarks.

Issue Release: 2021

Mononucleotide repeat expansions with non-natural polymerase substrates.

Issue Release: 2021

The Startling Role of Mismatch Repair in Trinucleotide Repeat Expansions.

Issue Release: 2021

Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loops.

Issue Release: 2021

High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.

Issue Release: 2021

Evaluation of ArmedXpert software tools, MixtureAce and Mixture Interpretation, to analyze MPS-STR data.

Issue Release: 2021

What Are the Emerging Technologies Involving Wavelengths in Cancer Treatment?

What are the Challenges in Targeting Gene Amplifications?

Can software predict cancer progression?

What are the Challenges in Enhancing Diagnostic Accuracy?

What Types of Cancer are Associated with LANA?

What Role Does Nutrition Play in Cancer Among the Poor?

What Are the Key Epigenetic Mechanisms in Cancer?

How Do Carcinogens Work?

Is Music Therapy a Formal Part of Cancer Treatment?

What Are the Treatment Strategies for Residual Cancer Cells?

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