Can Targeting Actin Dynamics Be a Potential Cancer Therapy?
Given the pivotal role of actin dynamics in cancer cell motility, targeting actin regulatory proteins offers potential therapeutic strategies. Drugs that stabilize or destabilize actin filaments, or inhibit actin-related signaling pathways, are being explored to limit cancer cell invasion and metastasis. However, the ubiquitous nature of actin in normal cellular functions poses challenges in developing selective therapies.
