Can Targeting Microfilaments Offer Therapeutic Benefits?
Given their pivotal role in cancer cell motility and invasion, microfilaments present a potential target for cancer therapy. Drugs that disrupt actin filament polymerization, such as cytochalasins and latrunculins, have been investigated for their ability to inhibit cancer cell movement. However, due to the essential functions of microfilaments in normal cells, these therapies must be carefully designed to minimize adverse effects. Research continues to explore how targeting microfilaments can be harnessed to improve cancer treatment outcomes.