What is the Process for Developing a Personalized Cancer Vaccine?
The development process typically involves several key steps:
Tumor Sequencing: A sample of the patient's tumor is sequenced to identify mutations and neoantigens. Neoantigen Selection: Bioinformatics tools are used to predict which neoantigens are most likely to produce a strong immune response. Vaccine Formulation: The selected neoantigens are synthesized and formulated into a vaccine. Administration: The vaccine is administered to the patient, often in combination with other treatments like immunotherapy or checkpoint inhibitors.
