Alternative Lengthening Of Telomeres - Cancer Science

Relevant Publications

Extrachromosomal telomere DNA derived from excessive strand displacements.

Issue Release: 2024

HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability.

Issue Release: 2024

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.

Issue Release: 2024

SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML.

Issue Release: 2024

Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas.

Issue Release: 2024

Investigating the structural and functional consequences of germline single nucleotide polymorphisms located in the genes of the alternative lengthening of telomere (ALT) pathway.

Issue Release: 2024

The Role of Glia Telomere Dysfunction in the Pathogenesis of Central Nervous System Diseases.

Issue Release: 2024

SUMO promotes DNA repair protein collaboration to support alternative telomere lengthening in the absence of PML.

Issue Release: 2024

Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres).

Issue Release: 2024

Alternative Lengthening of Telomeres in Yeast: Old Questions and New Approaches.

Issue Release: 2024

Effects of p53 and ATRX inhibition on telomeric recombination in aging fibroblasts.

Issue Release: 2024

Alternative lengthening of telomeres is seen in a proportion of oligodendrogliomas and is associated with a worse prognosis.

Issue Release: 2024

METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.

Issue Release: 2024

TERRA and the alternative lengthening of telomeres: a dangerous affair.

Issue Release: 2024

Telomere dynamics in human pluripotent stem cells.

Issue Release: 2024

Vorinostat, temozolomide or bevacizumab with irradiation and maintenance BEV/TMZ in pediatric high-grade glioma: A Children\'s Oncology Group Study.

Issue Release: 2024

The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients.

Issue Release: 2024

Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair.

Issue Release: 2024

BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response.

Issue Release: 2024

Novel role for Ddx39 in differentiation and telomere length regulation of embryonic stem cells.

Issue Release: 2024

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