Yes, certain fats are considered protective against cancer. Omega-3 fatty acids, found in fatty fish like salmon and mackerel, as well as flaxseeds and walnuts, have been shown to have anti-inflammatory properties and may reduce the risk of breast, prostate, and colorectal cancers. Monounsaturated fats, present in olive oil, avocados, and nuts, are also associated with a lower risk of cancer.