Creb Binding Protein (cbp) - Cancer Science

Relevant Publications

Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong Antitumor Activity.

Issue Release: 2024

CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC.

Issue Release: 2024

Discovery of a Promising CBP/p300 Degrader XYD129 for the Treatment of Acute Myeloid Leukemia.

Issue Release: 2024

Maintenance of thermogenic adipose tissues despite loss of the H3K27 acetyltransferases p300 or CBP.

Issue Release: 2024

Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles.

Issue Release: 2024

Targeting Wnt signaling for improved glioma immunotherapy.

Issue Release: 2024

SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP.

Issue Release: 2024

CREB-Binding Protein Regulates Cocaine- and Amphetamine-Regulated Transcript Peptide Expression in the Lateral Hypothalamus: Implication in Reward and Reinforcement.

Issue Release: 2024

SMARCA2 and SMARCA4 Participate in DNA Damage Repair.

Issue Release: 2024

Validation of selective catalytic BmCBP inhibitors that regulate the Bm30K-24 protein expression in silkworm, Bombyx mori.

Issue Release: 2024

MicroRNA‑4327 regulates TGF‑β1 stimulation of matrix metalloproteinase‑13 expression via CREB‑binding protein‑mediated Runx2 acetylation in human osteoblasts.

Issue Release: 2024

Comparative proteomic analysis of regenerative mechanisms in mouse retina to identify markers for neuro-regeneration in glaucoma.

Issue Release: 2024

PBA2, a novel inhibitor of the β-catenin/CBP pathway, eradicates chronic myeloid leukemia including BCR-ABL T315I mutation.

Issue Release: 2024

The Neuronal Hypofunction of Subdivisions of the Prefrontal Cortex Shows Differential Effects on Contingency Judgment Learning to Gauge Fear Responses.

Issue Release: 2024

Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain.

Issue Release: 2024

KLF4 and CD55 expression and function depend on each other.

Issue Release: 2024

Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma.

Issue Release: 2024

CBP/P300 Inhibition Impairs CD4+ T Cell Activation: Implications for Autoimmune Disorders.

Issue Release: 2024

Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma.

Issue Release: 2024

Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration.

Issue Release: 2024

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