testicles - Cancer Science

What is Testicular Cancer?

Testicular cancer is a type of cancer that originates in the testicles, which are part of the male reproductive system. The testicles are responsible for producing sperm and the hormone testosterone. This type of cancer is relatively rare but is the most common cancer in young men aged 15 to 35.

Types of Testicular Cancer

There are primarily two types of testicular cancer: seminomas and non-seminomas. Seminomas grow more slowly and respond well to radiation therapy. Non-seminomas tend to grow more quickly and include several different subtypes such as embryonal carcinoma, yolk sac carcinoma, choriocarcinoma, and teratoma.

Risk Factors

Several risk factors can increase the likelihood of developing testicular cancer:

Undescended testicle (cryptorchidism)
Family history of testicular cancer
HIV infection
Previous history of testicular cancer
Age (most common in men aged 15-35)
Race (more common in white men than in men of other races)

Symptoms

Common symptoms of testicular cancer include:

A lump or swelling in the

Relevant Publications

Ranolazine Ameliorates T1DM-Induced Testicular Dysfunction in Rats; Role of NF-κB/TXNIP/GSDMD-N/IL-18/Beclin-1 Signaling Pathway.

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Polyorchidism in a young Sprague-Dawley rat.

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Use of Knotless Barbed Sutures in Laparoscopic Inguinal Hernioplasty in Horses: 40 Cases.

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Radioprotective Effect of Selenium Nanoparticles: A Mini Review.

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Comparison of Testicular Sonography and Elastography Findings With Semen Parameters in Cases Investigated for Infertility.

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Pediatric Myeloid Sarcoma of the Testes Treated With Surgery and Adjuvant Radiation Therapy.

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Diosmin protects the testicles from doxorubicin-induced damage by increasing steroidogenesis and suppressing oxido-inflammation and apoptotic mediators.

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The protective effect of Ozone on the mice testicular damage induced by methotrexate.

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Observations on the anatomy of the funiculus spermaticus and the testis in Brachyteles sp. (SPIX, 1823) primates - Atelidae.

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A rare case report of orchiopexy and hysterectomy in an Afghan boy with persistent Müllerian duct syndrome.

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Evaluation of as a Therapeutic Agent against Sodium Arsenic-Induced Testicular Toxicity in a Male Rats Model.

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Comparison of sperm retrieval rate between superficial and deep dissection during microscopic testicular sperm extraction.

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[First line management of infertile couple. Guidelines for Clinical Practice of the French College of Obstetricians and Gynecologists 2022.]

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Morphometric study applied to testicular and epididymis hydatids torsion.

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Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism.

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The Utilization of Fine Needle Vasography to Localize Obstruction of the Male Reproductive Tract.

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Effects of edaravone on testicular torsion-detorsion injury in rats.

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Surgical treatment of cryptorchidism: current insights and future directions.

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Clinically functioning gonadotropin-secreting pituitary adenoma.

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Pleural mesothelioma (PMe): The evolving molecular knowledge of a rare and aggressive cancer.

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