How Do Genetic Mutations Influence Cancer Subtypes?
Genetic mutations play a significant role in defining cancer subtypes. Specific mutations can drive the development and progression of cancer, and identifying these mutations can provide insights into the tumor's behavior and response to treatment. For example:
Mutations in the BRCA1 and BRCA2 genes are associated with certain subtypes of breast and ovarian cancer. Mutations in the EGFR gene are commonly found in certain subtypes of lung cancer. Mutations in the KRAS gene are often seen in colorectal cancer.