Are There Any Limitations to Near Infrared Fluorescence?
While NIRF is a powerful tool, it has some limitations: - Limited Penetration Depth: Although NIRF penetrates deeper than visible light, it still has a limited depth of penetration compared to modalities like MRI or CT scans. - Dye Safety: The safety and biocompatibility of fluorescent dyes need to be thoroughly evaluated before clinical use. - Technical Complexity: The equipment and expertise required for NIRF imaging can be costly and complex, limiting its widespread adoption.
