Are There Any Limitations to Using dbSNP in Cancer Research?
While dbSNP is a valuable resource, it is not without limitations. One major limitation is that it primarily includes data from populations of European descent, which can bias the findings. Additionally, not all SNPs cataloged in dbSNP are functionally annotated, making it challenging to determine their impact on cancer. Lastly, the sheer volume of data can be overwhelming, requiring sophisticated bioinformatics tools for effective analysis.
