Despite their potential, MWCNTs come with challenges and risks: 1. Toxicity: There are concerns about the long-term toxicity of MWCNTs, as they can induce inflammatory responses and oxidative stress. 2. Biodegradability: MWCNTs are not easily biodegradable, which raises concerns about their accumulation in the body. 3. Functionalization: Ensuring that MWCNTs are properly functionalized to avoid immune system rejection is a critical challenge.