Yes, there are several types of direct inhibitors, each targeting different molecular pathways or proteins. Some of the most common types include:
- Tyrosine Kinase Inhibitors (TKIs): Target enzymes that play a crucial role in the signaling pathways governing cell division and growth. - Proteasome Inhibitors: Interfere with the cell's protein degradation machinery, causing an accumulation of defective proteins that can lead to cell death. - PARP Inhibitors: Block the enzyme Poly (ADP-ribose) polymerase, which is involved in DNA repair, making cancer cells more susceptible to damage. - mTOR Inhibitors: Target the mTOR pathway, which is involved in cell metabolism, growth, and proliferation.
