Can Gene Amplification be Targeted for Cancer Treatment?
Yes, gene amplification can be targeted for cancer treatment. Targeted therapies that specifically inhibit the proteins produced by amplified genes have shown great promise. For example, tyrosine kinase inhibitors target amplified EGFR in lung cancer, while HER2 inhibitors are used in HER2-positive breast cancer. These treatments can be highly effective, especially when combined with other therapeutic approaches.