Understanding the cancer genome is essential for developing targeted therapies. Several technologies are used to study cancer genomes:
Next-generation sequencing (NGS): Allows for high-throughput sequencing of DNA, providing detailed information about mutations and other alterations. Whole-genome sequencing: Involves sequencing the entire genome, offering a comprehensive view of all genetic changes. Exome sequencing: Focuses on sequencing the coding regions of genes, where most disease-causing mutations occur. RNA sequencing (RNA-seq): Analyzes the transcriptome, providing insights into gene expression changes in cancer cells.
