The development of evidence-based guidelines involves several steps: 1. Systematic Review: A comprehensive review of existing research is conducted. 2. Assessment of Evidence Quality: Studies are evaluated for their methodological quality and relevance. 3. Recommendations Formulation: Based on the evidence, recommendations are formulated. 4. Peer Review and Public Comment: Draft guidelines are reviewed by experts and made available for public comment. 5. Publication and Dissemination: Final guidelines are published and disseminated to healthcare providers.