Diagnosis involves a combination of clinical evaluation and diagnostic tests:
- Blood Tests: Can reveal abnormal levels of lymphocytes. - Bone Marrow Biopsy: Used to identify cancerous cells in the bone marrow. - Imaging Studies: CT, MRI, and PET scans help in identifying the extent of the disease. - Lymph Node Biopsy: Examines lymph node tissue for cancerous cells. - Flow Cytometry and Cytogenetic Analysis: Characterize the specific types of cancer cells.