How are Signaling Pathways Targeted in Cancer Therapy?
Cancer therapies target signaling pathways through various strategies, including small molecule inhibitors, monoclonal antibodies, and RNA-based therapies. These treatments aim to block the aberrant signals driving cancer progression. For example, Tyrosine kinase inhibitors (TKIs) are used to target the BCR-ABL fusion protein in chronic myeloid leukemia, and monoclonal antibodies like trastuzumab target the HER2 receptor in breast cancer.
