Detection of somatic mutations involves sophisticated techniques such as:
- Next-Generation Sequencing (NGS): Allows for comprehensive analysis of the cancer genome. - Whole Exome Sequencing (WES): Focuses on the coding regions of the genome where most pathogenic mutations occur. - Targeted Sequencing: Analyzes specific genes known to be involved in cancer. - Comparative Genomic Hybridization (CGH): Detects CNVs by comparing tumor DNA to normal DNA.
