Diagnosis of trophoblastic diseases often involves several steps. Initially, a pelvic exam may reveal abnormalities. Ultrasound imaging is crucial for assessing the nature of the growth. Blood tests measuring the levels of human chorionic gonadotropin (hCG) are also essential. Elevated hCG levels can indicate the presence of these diseases. In some cases, a biopsy or curettage may be performed to obtain tissue samples for histological examination.