How Can CTL Responses Be Enhanced in Cancer Therapy?
Several strategies are being investigated to enhance CTL responses against cancer:
Combination Therapies: Combining checkpoint inhibitors with traditional therapies like chemotherapy or radiation can enhance CTL activation. Vaccines: Cancer vaccines aim to stimulate CTLs by presenting tumor antigens in a highly immunogenic context. Genetic Engineering: CTLs can be genetically modified to express chimeric antigen receptors (CARs) that enhance their specificity and killing capacity.
