How Can Genomic Variants Influence Cancer Prognosis?
Certain genomic variants are associated with poor or favorable prognoses in cancer patients. For example, mutations in the TP53 gene are often linked with a more aggressive disease and poorer outcomes. Conversely, the presence of mutations in the EGFR gene in non-small cell lung cancer is associated with responsiveness to EGFR inhibitors, often leading to better outcomes.
