How Can Metabolic Pathways be Targeted for Cancer Therapy?
Targeting altered metabolic pathways offers a promising approach for cancer therapy. Several metabolic inhibitors are being developed and tested in clinical trials. For instance, inhibitors of glycolysis, such as hexokinase inhibitors, aim to block the primary energy source of cancer cells. Similarly, drugs targeting lipid synthesis or amino acid metabolism are being explored to cut off the supply of essential building blocks required for tumor growth.