How Can the Tumor Microenvironment Influence Resistance?
The [tumor microenvironment](href) comprises various cells, molecules, and blood vessels that surround and interact with the tumor. Elements such as hypoxia (low oxygen levels), acidic pH, and the presence of stromal cells can protect cancer cells from treatments. However, interventions that modify these environmental factors, such as normalizing blood vessels to improve drug delivery or using agents that target stromal cells, can reduce resistance.