In basket trials, patients with different types of cancers but with the same genetic mutation or molecular target receive the same treatment. For instance, if a particular mutation like the BRAF V600E is found in both melanoma and colorectal cancer, patients from both cancer types can be included in the same basket trial to test the efficacy of a targeted therapy. This type of trial leverages the commonality in the molecular profile to potentially fast-track the drug development process.
