How Do BRCA1 and BRCA2 Mutations Increase Cancer Risk?
Mutations in these genes can lead to the development of cancer because the DNA repair process is compromised. This allows genetic mutations to accumulate, increasing the risk of cells becoming cancerous. Individuals with harmful mutations in BRCA1 or BRCA2 are at a significantly elevated risk for breast and ovarian cancer, as well as other types such as prostate and pancreatic cancer.
