How Do Complex Formulations Improve Drug Delivery?
Complex formulations improve drug delivery through various mechanisms:
Enhanced Permeability and Retention (EPR) Effect: Many tumors have leaky vasculature, allowing larger molecules like nanoparticles to accumulate preferentially in the tumor tissue. Targeted Delivery: Functionalization with antibodies, peptides, or small molecules can direct these formulations to specific cancer cell receptors. Controlled Release: Formulations can be designed to release their payload over an extended period or in response to specific stimuli, ensuring sustained therapeutic levels at the tumor site.
