Genetic mutations are one of the primary internal stimuli that can lead to cancer. Mutations in certain genes, such as oncogenes and tumor suppressor genes, can disrupt normal cellular functions and lead to uncontrolled cell growth. For example, mutations in the BRCA1 and BRCA2 genes are known to increase the risk of breast and ovarian cancers. These genetic changes can be inherited or acquired due to various factors, including exposure to carcinogens or errors during DNA replication.
