How Do Genetic Mutations Impact Tumor Aggressiveness?
Genetic mutations play a critical role in determining a tumor's aggressiveness. Mutations in genes like TP53, BRCA1, and BRCA2 are often associated with more aggressive cancers. These mutations can lead to uncontrolled cell division and an increased ability for the tumor to invade surrounding tissues and organs. Additionally, some mutations may enable cancer cells to resist chemotherapy, further complicating treatment.
