How Do Hypoxia and Angiogenesis Contribute to Tumor Growth?
Hypoxia (low oxygen levels) is a common feature of solid tumors due to inadequate blood supply. Hypoxia can drive cancer progression by inducing the expression of genes involved in survival, angiogenesis, and metastasis. Angiogenesis, the formation of new blood vessels, is crucial for providing oxygen and nutrients to the growing tumor. Factors like VEGF play a significant role in promoting angiogenesis.