How Do Molecular Pathways Influence Cancer Progression?
Multiple molecular pathways are involved in cancer progression, including the PI3K/AKT pathway, the MAPK pathway, and the Wnt signaling pathway. Dysregulation in these pathways can lead to enhanced cell survival, proliferation, and metastasis. For instance, mutations in the PIK3CA gene activate the PI3K/AKT pathway, promoting tumor growth and resistance to apoptosis.