How do Nicotinic Receptor Antagonists Work in Cancer Treatment?
Nicotinic receptor antagonists can interfere with the signaling pathways that are crucial for cancer cell growth and survival. By blocking nAChRs, these antagonists can reduce cancer cell proliferation, induce apoptosis, and inhibit metastasis. Additionally, these drugs can enhance the efficacy of other cancer treatments, such as chemotherapy and radiotherapy, by sensitizing cancer cells to these treatments.