proteases

How Do Proteases Contribute to Cancer Progression?

Proteases contribute to cancer progression through various mechanisms. One of the primary roles is in the degradation of the extracellular matrix (ECM), which allows cancer cells to invade surrounding tissues and spread to distant sites (metastasis). This process is facilitated by different families of proteases, including matrix metalloproteinases (MMPs), serine proteases, and cysteine proteases.

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