PTMs can influence cancer development and progression in several ways:
Oncogene Activation: PTMs can activate oncogenes, leading to uncontrolled cell proliferation. Tumor Suppressor Inactivation: PTMs can inactivate tumor suppressor proteins, removing critical checks on cell growth. Signal Transduction: PTMs can modulate signaling pathways that regulate cell growth, survival, and differentiation. Epigenetic Changes: PTMs can alter the epigenetic landscape, affecting gene expression patterns that promote cancer.
