The initiation of a tumor typically begins with a series of genetic mutations that cause normal cells to transform into malignant ones. These mutations can result from various factors such as inherited genetic predispositions, exposure to carcinogens, and random cellular errors. Once a cell becomes cancerous, it can proliferate uncontrollably and form a primary tumor. The growth of the tumor is fueled by the cell cycle, a series of phases that cells go through to divide and multiply.