Cancer and its treatments can affect dexterity in several ways: 1. Peripheral Neuropathy: Chemotherapy drugs can cause peripheral neuropathy, leading to numbness, tingling, and loss of coordination in the hands and feet. 2. Lymphedema: Surgical removal of lymph nodes or radiation therapy can lead to lymphedema, swelling that impairs hand function. 3. Muscle Weakness: Cancer treatments can cause muscle weakness, making fine motor tasks challenging. 4. Pain and Inflammation: Pain and inflammation in hands and joints can also contribute to decreased dexterity.