Cancer can impact nerve function through several mechanisms: 1. Direct Invasion: Tumors can directly invade nerve tissues, leading to neuropathy. 2. Compression: Tumors may compress nerves or the spinal cord, causing impaired nerve function. 3. Paraneoplastic Syndromes: These are rare disorders triggered by an abnormal immune response to a cancerous tumor, resulting in nerve damage. 4. Chemotherapy: Certain chemotherapeutic agents are known to cause nerve damage. Drugs like cisplatin, paclitaxel, and vincristine are notorious for causing CIPN.