Cancer can lead to neuromuscular symptoms through several mechanisms: 1. Direct tumor invasion: Tumors can invade or compress nerves and muscles, leading to symptoms. 2. Paraneoplastic syndromes: These are autoimmune responses where the bodyâs immune system attacks its own nervous or muscular tissues in response to cancer. 3. Chemotherapy and radiation: Treatments can damage nerves and muscles, leading to neuropathy and myopathy. 4. Metabolic imbalances: Cancer can cause metabolic changes that affect neuromuscular function.