Several mechanisms can lead to respiratory distress in cancer patients: - Tumor Growth: Tumors in the lungs or mediastinum can obstruct airways, making it difficult to breathe. - Pleural Effusion: Accumulation of fluid in the pleural space can compress the lungs. - Metastasis: Cancer spreading to the lungs from other body parts can impair lung function. - Treatment Side Effects: Radiation therapy, chemotherapy, and other treatments can cause inflammation and damage to lung tissue.