Cancer resistance can develop through several mechanisms:
Genetic Mutations: Cancer cells can acquire genetic mutations that allow them to survive despite the presence of anti-cancer drugs. Drug Efflux: Cancer cells may develop the ability to pump drugs out of their cells using efflux pumps, reducing the drug's effectiveness. Drug Inactivation: Some cancer cells can produce enzymes that inactivate drugs before they can exert their effects. Altered Drug Targets: Cancer cells can modify the molecular targets of drugs, rendering them less effective. Cell Death Evasion: Cancer cells may evade programmed cell death, or apoptosis, which is often induced by cancer therapies.
