How Does Cell Migration Contribute to Cancer Progression?
In cancer, cell migration is often deregulated, leading to the invasion of cancer cells into surrounding tissues and their subsequent dissemination to other parts of the body. This involves a series of steps, starting with the detachment of cancer cells from the primary tumor, followed by their invasion through the extracellular matrix, and eventually their intravasation into blood vessels or lymphatic systems. Once in circulation, these cells can extravasate into new tissues and establish secondary tumors.