How Does Genetic Diversity Affect Cancer Susceptibility?
Genetic diversity among humans results in different responses to carcinogens and cancer treatments. Polymorphisms in genes involved in DNA repair, cell cycle regulation, and apoptosis can affect an individual's ability to prevent or repair cellular damage that leads to cancer. For example, individuals with variations in the TP53 gene, known as the "guardian of the genome," may have a higher risk of developing various cancers.
